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临床试验/NCT02603627
NCT02603627
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Cross-sectional Study to Compare the Prevalence of Chronic Obstructive Pulmonary Disease (COPD) in Patients Newly Diagnosed With Lung Cancer, Compared to Controls

Guy's and St Thomas' NHS Foundation Trust1 个研究点 分布在 1 个国家目标入组 200 人2015年12月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
COPD
发起方
Guy's and St Thomas' NHS Foundation Trust
入组人数
200
试验地点
1
主要终点
Prevalence of COPD in lung cancer compared to controls, using spirometry to diagnose COPD.
最后更新
10年前

概览

简要总结

This study will investigate the prevalence of chronic obstructive pulmonary disease (COPD) in patients who are newly diagnosed with lung cancer and compare it to the prevalence of COPD in controls recruited from a smoking cessation clinic.

详细描述

Chronic obstructive pulmonary disease (COPD) is a breathing problem that some people develop. Usually it is caused by smoking. Damage to the lungs means that patients are at risk of more chest infections and are unable to exercise like healthy individuals. They may also have a long-standing cough. COPD is diagnosed by testing lung function, usually using a small device called a spirometer. COPD is becoming a better understood condition. It is known that the lungs of patients with COPD are sometimes inflamed. This is important because inflammation is associated with some types of cancer, including lung cancer. The investigators are interested in whether COPD puts people at higher risk of lung cancer. They would like to find out how common COPD is in patients who have lung cancer. The investigators would also like to find out how common COPD is in patients who are not known to have lung cancer (comparison group). This will help them interpret their results better as investigators will be able to compare the two groups.

注册库
clinicaltrials.gov
开始日期
2015年12月
结束日期
2016年8月
最后更新
10年前
研究类型
Observational
性别
All

研究者

入排标准

入选标准

  • Informed consent
  • Aged over 18
  • Lung cancer group: new diagnosis of lung cancer, with spirometry results available Control group: spirometry result available or obtained

排除标准

  • Patient refusal
  • Age under 18
  • Control group: pre-existing lung cancer

结局指标

主要结局

Prevalence of COPD in lung cancer compared to controls, using spirometry to diagnose COPD.

时间窗: Up to nine months

次要结局

  • Comparison of the proportion of individuals with an emphysematous phenotype to the proportion of individuals with a bronchitic phenotype.(Up to nine months)
  • Comparison of the proportion of small cell tumours to non-small cell tumours in patients with lung cancer and COPD.(Up to nine months)

研究点 (1)

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