Cross-sectional Study to Compare the Prevalence of Chronic Obstructive Pulmonary Disease (COPD) in Patients Newly Diagnosed With Lung Cancer, Compared to Controls
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Prevalence of COPD in lung cancer compared to controls, using spirometry to diagnose COPD.
研究概览
简要总结
This study will investigate the prevalence of chronic obstructive pulmonary disease (COPD) in patients who are newly diagnosed with lung cancer and compare it to the prevalence of COPD in controls recruited from a smoking cessation clinic.
详细描述
Chronic obstructive pulmonary disease (COPD) is a breathing problem that some people develop. Usually it is caused by smoking. Damage to the lungs means that patients are at risk of more chest infections and are unable to exercise like healthy individuals. They may also have a long-standing cough.
COPD is diagnosed by testing lung function, usually using a small device called a spirometer.
COPD is becoming a better understood condition. It is known that the lungs of patients with COPD are sometimes inflamed. This is important because inflammation is associated with some types of cancer, including lung cancer.
The investigators are interested in whether COPD puts people at higher risk of lung cancer. They would like to find out how common COPD is in patients who have lung cancer. The investigators would also like to find out how common COPD is in patients who are not known to have lung cancer (comparison group). This will help them interpret their results better as investigators will be able to compare the two groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Informed consent
- •Aged over 18
- •Lung cancer group: new diagnosis of lung cancer, with spirometry results available Control group: spirometry result available or obtained
排除标准
- •Patient refusal
- •Age under 18
- •Control group: pre-existing lung cancer
结局指标
主要结局
Prevalence of COPD in lung cancer compared to controls, using spirometry to diagnose COPD.
时间窗: Up to nine months
次要结局
- Comparison of the proportion of individuals with an emphysematous phenotype to the proportion of individuals with a bronchitic phenotype.(Up to nine months)
- Comparison of the proportion of small cell tumours to non-small cell tumours in patients with lung cancer and COPD.(Up to nine months)