Predictability of Preoperative Carotid Artery Corrected Flow Time for Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Occurrence of Hypotension
研究概览
简要总结
The purpose of this study was to investigate the incidence of hypotension after spinal anesthesia in patients undergoing cesarean section as predicted by preoperative carotid artery corrected flow time measured by Doppler ultrasound. Before entering the operation room, Two inspectors perform two measurements of carotid artery corrected blood flow time respectively, and an average of the four measurements is calculated and analyzed. At this time, the patient's posture is supine, and the head is turned about 30 degrees to the left. Corrected blood flow time (FTc) is measured using carotid ultrasound as previously described by Blehar and colleagues. Corrected blood flow time is calculated by Bazett's formular and Wodey's formular by evaluating a single cycle after several successive cycles have reached a stable and acceptable quality level.
The occurrence of hypotension is recorded from the spinal anesthetic injection until the fetus is delivered.
The definition of hypotension after spinal anesthesia is that the systolic blood pressure drops to 80 mmHg, less than 75% of the baseline value, or even if it does not meet the former criteria, symptoms that are consistent with hypotension (dizziness, dizziness, dyspnea, nausea or vomiting).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Uncomplicated singleton full-term parturients undergoing cesarean delivery
- •age 20~40
- •ASA class 1~3
排除标准
- •Emergency surgery
- •Placenta previa
- •Preeclampsia or Preeclampsia
- •Cardiovascular or cerebrovascular disease
- •Morbid obesity with a body mass index (BMI) of 40 kg / m2 or higher
- •Gestational age <36 or ≥ 41 weeks
- •Contraindications to spinal anesthesia
- •Carotid stenosis> 50% (angiography, CT angiography, MR angiography, or duplex ultrasonography)
- •Basal systolic blood pressure> 160 mmHg
- •The preoperative examination revealed that the electrocardiogram was not normal sinus rhythm
- •Chronic kidney disease (eGFR <60 mL / min / 1.73 m2)
- •If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
结局指标
主要结局
Occurrence of Hypotension
时间窗: from the spinal anesthetic injection until the fetus is delivered.
The definition of hypotension after spinal anesthesia is that the systolic blood pressure drops to 80 mmHg, less than 75% of the baseline value , or even if it does not meet the former criteria, symptoms that are consistent with hypotension (dizziness, dizziness, dyspnea, nausea or vomiting) .
次要结局
- The systolic blood pressure difference(from the spinal anesthetic injection until the fetus is delivered.)