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Clinical Trials/ACTRN12615000571572
ACTRN12615000571572
Suspended
Phase 1

The effectiveness of a combination of Metformin and Atrovastatin compared with each drug alone and placebo in modulating tumour aggressiveness in men with high risk prostate cancer undergoing radical prostatectomy

niversity of Queensland Centre for Clinical Research0 sites80 target enrollmentJune 3, 2015
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ConditionsProstate cancerCancer - Prostate

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Prostate cancer
Sponsor
niversity of Queensland Centre for Clinical Research
Enrollment
80
Status
Suspended
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 3, 2015
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
Male

Investigators

Sponsor
niversity of Queensland Centre for Clinical Research

Eligibility Criteria

Inclusion Criteria

  • •Patients will be eligible for the trial if they are adult men aged 40 to 80 years who have a PI\-RADSv2 (Prostate Imaging\-Reporting and Data System) score of 4 or 5 and proceed to prostate biopsy with an intention of having a prostatectomy for confirmed high\-risk prostate cancer

Exclusion Criteria

  • •Participants will be ineligible for the trial if they:
  • •\- have been taking any lipid (fats) or cholesterol\-lowering medication or blood\-glucose (sugar level)\-lowering drugs
  • •\- have experienced any unwanted effects with lipid or glucose\-lowering drugs previously
  • •\- have been considered by their urologist to be unsuitable for the research programme or involvement in the study is not consistent with the patient’s best interests
  • •\- are taking medications that could cross\-react with medications used in the trial

Outcomes

Primary Outcomes

Not specified

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