Correlation Between Intraocular Pressure Measurement by Tomometer and Anterior Chamber Depth Measurement by Ultrasound in Steep Trendelenberg Position During Robotic Assisted Surgery
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Changes in intraocular pressure measured by tonometer
研究概览
简要总结
Intra ocular pressure (IOP) may theoretically increase due to steep Trendelenberg position and studies showed that IOP reaches peak levels after steep Trendelenberg position on an average of 13 mmHg higher than preanesthesia induction values. Major determinants of IOP are aqueous humor flow, choroidal blood volume, central venous pressure and extra ocular muscle tone.
Hassen GW et al measured anterior chamber depth in 2 patients with glaucoma and compared the anterior chamber depth (ACD) with the intraocular pressure measured by tonometer. They concluded that bedside ultrasound could be useful in evaluating patient with suspected increased IOP, who are unable to open their eyes.
详细描述
Intra ocular pressure (IOP) may theoretically increase due to steep Trendelenberg position and studies showed that IOP reaches peak levels after steep Trendelenberg position on an average of 13 mmHg higher than preanesthesia induction values. Major determinants of IOP are aqueous humor flow, choroidal blood volume, central venous pressure and extra ocular muscle tone. During the robotic surgery there are two theories explaining the increase of IOP, first, gravitational forces increase central venous pressure which in turn affect orbital venous pressure and increase IOP. Second, intraperitoneal carbon dioxide causes increased choroidal blood volume which may result in IOP increase. One study reported that low end tidal carbon dioxide was a significant predictor of the IOP increase. Continuous absorption of carbon dioxide from peritoneum and increased pressure on diaphragm results in lower delivered tidal volumes and subsequently increased arterial carbon dioxide levels leading to increased choroidal blood flow and increased IOP.
Hassen GW et al measured anterior chamber depth in 2 patients with glaucoma and compared the anterior chamber depth (ACD) with the intraocular pressure measured by tonometer. They concluded that bedside ultrasound could be useful in evaluating patient with suspected increased IOP, who are unable to open their eyes. It can also be used for serial examination and follow-up of treatment success. They also mentioned that, it is necessary to conduct a prospective study with a larger sample size, to evaluate if there is agreement between measurements using a tonometer and measurements of the ACD using ultrasound. In addition, it is essential to determine the cut off normal ACD for evaluation of IOP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA class I-III
- •Urological cancer patients under going robotic assisted surgeries.
- •Gastrointestinal cancer patients under going robotic assisted surgeries,
- •Gynecological cancer patients under going robotic assisted surgeries,
排除标准
- •ASA class IV and above
- •Patients with a history of glaucoma.
- •Patients with corneal disease, retinal vascular disease.
研究组 & 干预措施
IOP by tomoneter and ultrasound
Intraocular pressure will be measured by electronic tomometer (tonopen) at different point of time after induction of anaesthesia in patients undergoing robotic assisted surgery under steep Trendelenberg position. Anterior chamber depth will be measured by ultrasound at the same time intervals.
干预措施: IOP by tonometer (Device)
IOP by tomoneter and ultrasound
Intraocular pressure will be measured by electronic tomometer (tonopen) at different point of time after induction of anaesthesia in patients undergoing robotic assisted surgery under steep Trendelenberg position. Anterior chamber depth will be measured by ultrasound at the same time intervals.
干预措施: Anterior chamber depth measurement by ultrasound (Device)
结局指标
主要结局
Changes in intraocular pressure measured by tonometer
时间窗: Just after induction of anesthesia, every 2 hours during surgery and immediately after surgery
Intra operative recordings of IOP will be after induction and thereafter will be measured every 2 hours and at the end of surgery.
Changes in anterior chamber depth measured by ultrasound.
时间窗: Just after induction of anesthesia, every 2 hours during surgery and immediately after surgery
Intra operative recordings of anterior chamber depth will be measured after induction of anaesthesia, every 2 hours intraoperatively and at end of surgery.
次要结局
- Time dependent changes in anterior chamber depth during prolonged trendelenberg position.(Just after induction of anesthesia, every 2 hours during surgery and immediately after surgery)
- Time dependent changes in IOP during prolonged steep Trendelenberg position.(Just after induction of anesthesia, every 2 hours during surgery and immediately after surgery)
研究者
Sohan Lal Solanki
Assistant Professor, Department of Anesthesiology, Critical Care and Pain
Tata Memorial Centre
