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Clinical Trials/NCT06027034
NCT06027034
Active, not recruiting
Not Applicable

Effectiveness of a Digital Health Application for Psoriasis: Randomized Controlled Trial

Gaia AG1 site in 1 country348 target enrollmentSeptember 4, 2023
ConditionsPsoriasis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psoriasis
Sponsor
Gaia AG
Enrollment
348
Locations
1
Primary Endpoint
Health-Related Quality of Life
Status
Active, not recruiting
Last Updated
8 months ago

Overview

Brief Summary

This clinical trial with 348 patients with psoriasis aims to investigate the effectiveness of a self-guided online program for patients with psoriasis.

Patients will be randomized and allocated in a 1:1 ratio to either an intervention group, in which they will receive 12-month-access to an online program for psoriasis in addition to treatment as usual (TAU, n = 174), or to a control group, in which they will receive only TAU (n = 174). TAU is defined as any therapy prescribed or recommended by the GP or specialists (e.g. dermatologist, psychiatrist), which may include topical therapy, phototherapy, pharmacotherapy, psychosocial therapy, etc.

Registry
clinicaltrials.gov
Start Date
September 4, 2023
End Date
December 1, 2026
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Gaia AG
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years
  • Presence of psoriasis vulgaris or psoriatic arthritis
  • Submission of a specialist medical certificate attesting to the presence of at least one of the following ICD-10-GM diagnoses: Psoriasis vulgaris (L 40.0, L 40.7), Psoriatic arthritis (L40.5, M07.x)
  • Impaired health-related quality of life (DLQI \> 10)
  • Consent to participate
  • Sufficient understanding of the German language

Exclusion Criteria

  • Presence of another subtype of psoriasis (pustular psoriasis, guttate psoriasis, inverse psoriasis, erythrodermic psoriasis, or drug-induced psoriasis) or psoriatic arthritis without skin involvement
  • Presence of malignancies
  • Presence of other chronic diseases with strong negative influence on quality of life
  • Currently undergoing psychiatric treatment / current presence of a severe psychiatric diagnosis
  • Insufficient language and/or IT skills

Outcomes

Primary Outcomes

Health-Related Quality of Life

Time Frame: 3 months

Total score of the Dermatology Life Quality Index (DLQI). Total score ranging from 0-30; higher scores mean a worse outcome.

Secondary Outcomes

  • Psoriasis Severity(3 months, 6 months, 12 months)
  • Health-Related Quality of Life(6 months, 12 months)
  • Depressive Symptoms(3 months, 6 months, 12 months)
  • Body Surface Area (BSA)(3 months, 6 months, 12 months)

Study Sites (1)

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