Impact of selective alpha 1A receptor antagonists on the pupil size after instillation of tropicamide 0.5% and phenylephrine 10%
- Conditions
- Impact of selective alpha 1A receptor antagonists on the pupil size after instillation of tropicamide 0.5% and phenylephrine 10%Therapeutic area: Diseases [C] - Eye Diseases [C11]
- Registration Number
- EUCTR2015-003064-36-AT
- Lead Sponsor
- Vienna Institute for Research in Ocular Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion criteria for the study group
-Age 21 and older
-Age-related cataract
-therapy with systemic selective alpha 1A antagonists (tamsulosin)
-written informed consent to participation in the study
Inclusion criteria for the control group
-Age 21 and older
-Age-related cataract
-written informed consent to participation in the study
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion criteria for the study group
-Pregnancy (pregnancy test will be taken pre-operatively in women of reproductive age)
-Traumatic cataract
-Any ophthalmic pathology that could compromise the measurements
Exclusion criteria for the control group
-Pregnancy (pregnancy test will be taken pre-operatively in women of reproductive age)
-Traumatic cataract
-Any ophthalmic pathology that could compromise the measurements
-Current or previous therapy with systemic alpha 1A antagonists
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method