A study to observe changes of nerve conduction and symptom findings in people with carpal tunnel syndrome before and after treatment with methylprednisolone

Completed

• Conditions: Carpal Tunnel Syndrome

• Registration Number: CTRI/2014/12/005273
• Lead Sponsor: Department of Physiology IPGMER

Brief Summary

This study was designed to assess the electrophysiological and clinical changes in patients with Carpal Tunnel Syndrome before and after treatment with single dose local injection of methylprednisolone into each affected carpal tunnel.It was conducted at IPGME&R, Kolkata.We recruited 30 patients of whom finally 18 completed the study. Assessment was done at  intervals designated above. It was found that a statistically significant reduction (p<0.01) in median motor and sensory conduction velocity were obtained 1 month after treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01-31
• Last Update Posted: 2014-07-12

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

patients with symptoms of pain, tingling,numbness in hands.

Exclusion Criteria

Diabetes,hypothyroidism,uraemia,pregnancy,previous treatment of CTS,fracture of wrist or hand.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Electrophysiological changes of median motor and sensory conduction velocity before and after treatment	Before and at 1,2 and 3 months after treatment

Secondary Outcome Measures

Name	Time	Method
assessment of symptom status before and after treatment	Before and at 1,2 and 3 months after treatment

Trial Locations

Locations (1)

Department of Physiology IPGMER; 🇮🇳 Kolkata, WEST BENGAL, India

Department of Physiology IPGMER

🇮🇳Kolkata, WEST BENGAL, India

Dr Pinaki Das

Principal investigator

84363934049

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