Comparison of Emergency Department Preoxygenation Techniques in Healthy Volunteers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 主要终点
- Exhaled Oxygen Concentration
研究概览
简要总结
Four methods of preoxygenation will be compared in healthy volunteers
详细描述
After informed consent, each volunteer will undergo the following techniques:
Simple mask at "flush" flow (40-60 L/min) Non-rebreather mask at 15 L/min Non-rebreather mask at 60 L/min Bag valve mask with one way exhalation valve at 15 L/min
After 3 minutes, the exhaled oxygen will be measured with an oxygen sensor
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 18 years old
排除标准
- •Any active respiratory pathology (asthma, chronic obstructive pulmonary disease, other lung disease, smoking history more than 5 years)
研究组 & 干预措施
Preoxygenation
All participants were enrolled in a single arm in which they underwent 4 interventions in series: 1) Simple mask at 60 L/min for 3 minutes 2) Non-rebreather at 15 L/min for 3 min 3) Non-rebreather at 60 L/min for 3 minutes 4) Bag valve mask at 15 L/min for 3 minutes
干预措施: Preoxygenation (Device)
结局指标
主要结局
Exhaled Oxygen Concentration
时间窗: Immediately after 3 minutes of oxygen supplementation
Subjects will blow into an oxygen sensor after each method (arm). The primary outcome will be a non-inferiority test between bag valve mask and non-rebreather at 60 L/min. The remaining tests will be completed for comparison, but not part of formal statistical testing.
次要结局
未报告次要终点
研究者
Brian Driver
Associate Research Director
Hennepin Healthcare Research Institute