EUCTR2004-001953-27-GB进行中(未招募)不适用
The Pharmacokinetics of Systemic Corticosteriods in Refractory Asthma
niversity Hospitals of Leicester NHS Trust0 个研究点目标入组 20 人开始时间: 2005年2月15日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Asthma cases:
- •1. Patients with refractory asthma (according to the American Thoracic Society Criteria for refractory asthma. Ref. American Journal of Respiratory and Critical Care Medicine 162(6):2341-2351)
- •1.Healthy volunteers with no respiratory symptoms
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. Current smokers or ex-smokers with more than 10-pack year smoking history
- •2. Significant other co-morbidity, including hepatic, renal or endocrine dysfunction
- •3. Pregnant or breast feeding women
- •4. Concurrent oral medication likely to interfere with prednisolone pharmacokinetics, e.g. anti-convulsants
- •5. Concurrent oral prednisolone at a dose of more than 10mg per day
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