PACTR202401599878859已完成3 期
Carotid artery compression in preventing postoperative cognitive dysfunction in patients undergoing mitral valve replacement surgery: A randomized clinical trial
Cairo University Hospitals0 个研究点目标入组 120 人开始时间: 2023年12月31日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)（—）
- 性别
- All
入选标准
- •Patients scheduled for mitral valve replacement surgery
- •Patients aged 18-60 years
排除标准
- •Disturbed Conscious Level (Glasgow Coma Scale less than 15)
- •Substance abuse
- •MMSE score less than 24 points
- •Emergency cases
- •Patients unable to read and write
- •Previous strokes or transient ischemic attacks
- •Significant carotid artery stenosis more than 50 %
- •Previous serious psychiatric or neurologic disorders
- •Previous atrial fibrillation within the last 6 months
- •Renal impairment, liver disease, or severe chronic obstructive pulmonary disease
- •A drop in mean arterial blood pressure by more than 20% before bypass and a mean arterial blood pressure less than 60 mmHg during bypass
- •End tidal CO2 less than 35 mmHg or more than 40 mmHg
- •Partial pressure of oxygen less than 150 mmHg or more than 250 mmHg
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