Effect of Subanesthetic Dose Propofol Use Before Extubation on Recovery From Anesthesia, Agitation on Recovery, and Patient Satisfaction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Changing Preoperative Anxiety Score (STAI)
研究概览
简要总结
This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty. Emergence agitation refers to restlessness and confusion during early recovery from anesthesia, which may affect patient safety and surgical conditions. The study evaluates agitation levels, recovery characteristics, and patient-reported comfort following propofol administration compared with standard care.
详细描述
This study aims to evaluate whether administering a sub-anesthetic dose of propofol before extubation can reduce emergence agitation, enhance recovery characteristics, and improve patient comfort in adults undergoing rhinoplasty surgery. Emergence agitation is a common phenomenon during early recovery from general anesthesia and can involve restlessness, disorientation, and involuntary movements, potentially affecting patient safety and surgical outcomes. The study uses a randomized controlled design to compare peri-extubation responses between patients receiving low-dose propofol and those receiving standard care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages 18-65 years
- •Patients scheduled for rhinoplasty surgery
- •ASA physical status I-II
- •No respiratory tract infection
- •Provided written informed consent
排除标准
- •Refusal to participate
- •Presence of any respiratory tract infection
- •Younger than 18 or older than 65
- •ASA III-IV
- •Known allergy to study medications
- •Predicted difficult intubation
研究组 & 干预措施
Propofol Group
Sub-anesthetic dose of propofol (0.5 mg/kg) administered 10 minutes before extubation.
干预措施: Normal Saline (Placebo) (Other)
Control Group
Normal saline administered 10 minutes before extubation.
干预措施: Propofol (Sub-Anesthetic Dose) (Drug)
结局指标
主要结局
Changing Preoperative Anxiety Score (STAI)
时间窗: 15 minutes (T1-T2)
Comparison of the State-Trait Anxiety Inventory (STAI) state anxiety score measured in the preoperative waiting room (T1) with the STAI score 15 minutes after the palming technique (T2). The difference between the two time points is analyzed to assess the anxiety-reducing effect of the intervention.
次要结局
- Hemodynamic Parameter Changes(15 minutes (T1-T2))
研究者
Nureddin YUZKAT
Associate professor
Yuzuncu Yil University