Effect of Subanesthetic Dose Propofol Use Before Extubation on Recovery From Anesthesia, Agitation on Recovery, and Patient Satisfaction
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Yuzuncu Yil University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Changing Preoperative Anxiety Score (STAI)
Overview
Brief Summary
This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty. Emergence agitation refers to restlessness and confusion during early recovery from anesthesia, which may affect patient safety and surgical conditions. The study evaluates agitation levels, recovery characteristics, and patient-reported comfort following propofol administration compared with standard care.
Detailed Description
This study aims to evaluate whether administering a sub-anesthetic dose of propofol before extubation can reduce emergence agitation, enhance recovery characteristics, and improve patient comfort in adults undergoing rhinoplasty surgery. Emergence agitation is a common phenomenon during early recovery from general anesthesia and can involve restlessness, disorientation, and involuntary movements, potentially affecting patient safety and surgical outcomes. The study uses a randomized controlled design to compare peri-extubation responses between patients receiving low-dose propofol and those receiving standard care.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Ages 18-65 years
- •Patients scheduled for rhinoplasty surgery
- •ASA physical status I-II
- •No respiratory tract infection
- •Provided written informed consent
Exclusion Criteria
- •Refusal to participate
- •Presence of any respiratory tract infection
- •Younger than 18 or older than 65
- •ASA III-IV
- •Known allergy to study medications
- •Predicted difficult intubation
Arms & Interventions
Propofol Group
Sub-anesthetic dose of propofol (0.5 mg/kg) administered 10 minutes before extubation.
Intervention: Normal Saline (Placebo) (Other)
Control Group
Normal saline administered 10 minutes before extubation.
Intervention: Propofol (Sub-Anesthetic Dose) (Drug)
Outcomes
Primary Outcomes
Changing Preoperative Anxiety Score (STAI)
Time Frame: 15 minutes (T1-T2)
Comparison of the State-Trait Anxiety Inventory (STAI) state anxiety score measured in the preoperative waiting room (T1) with the STAI score 15 minutes after the palming technique (T2). The difference between the two time points is analyzed to assess the anxiety-reducing effect of the intervention.
Secondary Outcomes
- Hemodynamic Parameter Changes(15 minutes (T1-T2))
Investigators
Nureddin YUZKAT
Associate professor
Yuzuncu Yil University