Fall Risk Reduction in Multiple Sclerosis: Exercise Versus Behavior
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- Multiple Sclerosis
- 发起方
- University of Illinois at Urbana-Champaign
- 入组人数
- 37
- 试验地点
- 1
- 主要终点
- Fall incidence
- 状态
- 已完成
- 最后更新
- 11年前
概览
简要总结
Falls are a serious health concern for persons with multiple sclerosis (MS). Over 50% of persons with MS suffer a fall over a 6-month periodwith the majority of falls resulting in medical attention for injuries (i.e., lacerations, bone fractures, & head injuries). The effects of a fall are often compounded as it can lead to activity curtailment, physiological deconditioning, and institutionalization. Despite the importance of falls in persons with MS, the appropriate prevention strategies (i.e. rehabilitation approaches) are not clear. The purpose of this investigation is to determine whether exercise based or educational based interventions are more suited for fall prevention in older adults with MS.
详细描述
Falls are a serious health concern for persons with multiple sclerosis (MS). Over 50% of persons with MS suffer a fall over a 6-month periodwith the majority of falls resulting in medical attention for injuries (i.e., lacerations, bone fractures, \& head injuries). The effects of a fall are often compounded as it can lead to activity curtailment, physiological deconditioning, and institutionalization. Despite the importance of falls in persons with MS, the appropriate prevention strategies (i.e. rehabilitation approaches) are not clear. It is well known that causes of falls are multifactorial with over 400 risk factors identified. However, it is believed that these factors can be divided into two main classes: intrinsic (e.g. physiological factors) and extrinsic factors. For instance balance dysfunction, spasticity and muscle weakness are physiological risk factors for falls in MS . Behavioral fall risk factors in MS include choosing appropriate footwear, lighting and utilizing appropriate assistive device. There is evidence that both types of risk factors can be minimized with appropriately designed interventions in persons with MS and have been shown to reduce fall risk and incidence in other clinical populations. This has led to calls for the combination of exercise training program that targets specific, modifiable physiological risk factors and educational interventions targeting modifiable behavioral risk factors in persons with MS. However, there is minimal evidence that these interventions in isolation or combination actually reduce fall incidence or risk in persons with MS. This proposal seeks to determine the effectiveness of a combined exercise and educational rehabilitation strategy to prevent falls in persons with MS.
研究者
入排标准
入选标准
- •Definite multiple sclerosis diagnosis
- •ambulatory
- •aged 50-75 years of age
- •fallen within 12 months
排除标准
- •non-ambulatory
- •outside age range
- •no fall history
结局指标
主要结局
Fall incidence
时间窗: 3 months
次要结局
- Mobility(3 months)
- Balance(3 Months)
- Physiological Fall Risk(3 Months)