The Effect of Salpingectomy Operation on Ovarian Reserve

Completed

• Conditions: Ovarian Insufficiency

• Registration Number: NCT06903650
• Lead Sponsor: Dokuz Eylul University

Brief Summary

This study aimed to evaluate the effect of salpingectomy operation on ovarian reserve. Ovarian reserve was evaluated by measuring anti-mullerian hormone levels from serum samples taken from the patients before the operation and 6 weeks after the operation. Ovarian doppler flow were evaluated by measuring the ovarian artery pulsatility index with transvaginal ultrasonography preoperatively, postoperative days 2 and postoperative weeks 6 . In our study, it was determined that ovarian functions may be negatively affected in the acute period after salpingectomy operation.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-27
• Primary Completion: 2021-03-03
• Study Completion: 2021-06-05
• Status Verified: 2025-03
• Study First Submitted: 2025-03-21
• Study First Submitted QC: 2025-03-28
• Study First Posted: 2025-03-31
• Last Update Submitted: 2025-03-31
• Last Update Posted: 2025-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 31

Inclusion Criteria

1. Women between the ages of 37-45 with continuing menstrual cycles (37 and 45 included)
2. Patients who will undergo uterine surgery for benign reasons or who will undergo salpingectomy only due to hydrosalpinx, ectopic pregnancy, tubo-ovarian abscess
3. Patients who have not had ovarian surgery before
4. Those without menopause and premature ovarian failure
5. Patients who accept the study

Exclusion Criteria

1. Age younger than 37 or older than 45
2. Those who want to withdraw from the study
3. Those who do not come for follow-up examination
4. Use of drugs that affect ovarian reserve
5. Any surgical procedure performed on the ovaries during the operation
6. No menstrual bleeding in the last year
7. Patients who received radiotherapy and hormonal therapy within 3 months before surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
right ovarian arter pı	perioperative, postoperative days 2 , postoperative weeks 6	rate of 0,87/ 0,84/ 0,76
left ovarian arter pı	perioperative, postoperative days 2, postoperative weeks 6	rate of 0,89/ 0,79/ 0.80
AMH levels	perioperative-postoperative weeks 6	Concentration of 1 ng/mL / 0,79 ng/mL

Trial Locations

Locations (1)

Dokuz Eylul University School of Medicine; 🇹🇷 İzmir, Turkey