Airway Resistance Measurement in Children 3 to 6 Years of Age
- Conditions
- Airway Obstruction
- Interventions
- Other: airway resistance measurement
- Registration Number
- NCT02563210
- Lead Sponsor
- University Hospital, Brest
- Brief Summary
In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 130
- Child 3 to 6 years aged
- Height below 90 centimeters
- Opposition to participation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description airway resistance measurement airway resistance measurement interruption and plethysmography techniques airway resistance measurement at each routine visit
- Primary Outcome Measures
Name Time Method airway resistance measure by interruption technique (Rint) Day one Rint is performed using Spiroteq Dyn'R during a 100 ms occlusion and calculated using the linear back extrapolation method
- Secondary Outcome Measures
Name Time Method measure of bronchodilator response Day one Bronchodilator response is assessed with Rint and sRaw measurement
Trial Locations
- Locations (1)
CHRU de Brest
🇫🇷Brest, France