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Clinical Trials/NCT02563210
NCT02563210
Completed
Not Applicable

Interrupter Technique and Plethysmography Airway Resistance Measurement: Comparison of These Two Techniques for the Diagnosis of Airway Obstruction Diagnosis and Bronchodilation Response in Children 3 to 6 Years of Age

University Hospital, Brest1 site in 1 country130 target enrollmentOctober 19, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Airway Obstruction
Sponsor
University Hospital, Brest
Enrollment
130
Locations
1
Primary Endpoint
airway resistance measure by interruption technique (Rint)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.

Registry
clinicaltrials.gov
Start Date
October 19, 2015
End Date
May 29, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Child 3 to 6 years aged

Exclusion Criteria

  • Height below 90 centimeters
  • Opposition to participation

Outcomes

Primary Outcomes

airway resistance measure by interruption technique (Rint)

Time Frame: Day one

Rint is performed using Spiroteq Dyn'R during a 100 ms occlusion and calculated using the linear back extrapolation method

Secondary Outcomes

  • measure of bronchodilator response(Day one)

Study Sites (1)

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