Airway Resistance Measurement in Children 3 to 6 Years of Age

Not Applicable

Completed

• Conditions: Airway Obstruction

• Registration Number: NCT02563210
• Lead Sponsor: University Hospital, Brest

Brief Summary

In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-09-15
• Study First Submitted QC: 2015-09-28
• Study First Posted: 2015-09-30
• Study Start: 2015-10-19
• Primary Completion: 2017-05-29
• Study Completion: 2017-05-29
• Status Verified: 2017-06
• Last Update Submitted: 2019-04-10
• Last Update Posted: 2019-04-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

• Child 3 to 6 years aged

Exclusion Criteria

• Height below 90 centimeters
• Opposition to participation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
airway resistance measure by interruption technique (Rint)	Day one	Rint is performed using Spiroteq Dyn'R during a 100 ms occlusion and calculated using the linear back extrapolation method

Secondary Outcome Measures

Name	Time	Method
measure of bronchodilator response	Day one	Bronchodilator response is assessed with Rint and sRaw measurement

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France