Comparison of the effect of intraoperative fluids (plasmalyte vs sterofundin) during major oncological surgeries.

Rajiv Gandhi cancer institute1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2020年1月11日最近更新: 2021年9月17日

试验速览

阶段: 不适用
状态: 已完成
发起方: Rajiv Gandhi cancer institute
入组人数: 60
试验地点: 1
主要终点: pH and lactate levels in ABG

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Iv fluid is administered intra-operatively to maintain fluid and electrolyte haemostasis. This facilitates optimum tissue oxygen delivery. As serum lactate is a biomarker of severe tissue hypoperfusion, we compared the lactate levels at the end of surgery.

Plasmalyte and Sterofundin are balanced crystalloid solutions that are routinely used in our institute in intraoperative period. Till now there are very few studies comparing the effect of these two on perfusion or acid base status. However no study has been done in major surgeries.

研究设计

研究类型: Interventional
分配方式: Not Applicable
盲法: Not Applicable

入排标准

年龄范围: 18.00 Year(s) 至 70.00 Year(s)（—）
性别: All

入选标准

•patients undergoing major onco-surgeries.

排除标准

•patients with significant renal, cardiac, or liver impairment, electrolyte imbalance in preoperative evaluation.

结局指标

主要结局

pH and lactate levels in ABG

时间窗: At the start of surgery and at the time of haemostasis

次要结局

Heart rate, mean blood pressure, total amount of crystalloid required, colloid requirement, blood replaced,(Baseline, hourly intraoperatively till end of surgery)

研究者

发起方

Rajiv Gandhi cancer institute

申办方类型

Research institution and hospital

研究点 (1)

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