Ischemic preconditioning in the surgical treatment of brain tumors

Not Applicable

• Conditions: Perioperative ischemia in patients with brain tumors; C71.9; C79.3; I63.9; Brain, unspecified; Secondary malignant neoplasm of brain and cerebral meninges; Cerebral infarction, unspecified

• Registration Number: DRKS00010409
• Lead Sponsor: eurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-10-01
• Study Start: 2016-10-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients with suspected primary or metastatic brain tumor for which surgical resection is planned;
Consent to participate in the study;
Age> 18.

Exclusion Criteria

Non OP-enabled patient (from anesthesiological, medical or surgical view);
Patients who have to be operated immediately without extensive preoperative diagnosis;
Lack of surgical consent;
Lack of consent to participate in the study;
Pregnancy;
Age <18 years;
History of peripheral arterial disease (PAD) or DM with use of oral antidiabetics.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of postoperative ischemia validated with early postoperative cMRI (<72h)

Secondary Outcome Measures

Name	Time	Method
Volume of Ischemia (cMRT <72h). New postoperative (1 week) deficit. Clinical status assessed by KPS (1 week postoperative).