IRCT20100827004641N18CompletedPhase 2
Comparition the impact of intraarticular Steroid and intraarticular ozon on improving the symptoms of osteoarthritis of knee
Physical Medicibe and Rehabilitaion Research Center of Tabriz0 sites40 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Enrollment
- 40
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 45 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Moderate Knee Osteoarthritis (grade two or three based Radiographic classification (Kellegren and Lawrence)
- •Existence of symptoms in favor of Knee Osteoarthritis for at least 3 months
- •Minimum score of 3 in the criterion (VAS)
- •Absence of Inflammatory Rheumatic diseases
- •45 years old and older
- •Satisfaction of patients participating in the study
- •Failure to respond to Conservative drug treatments and physiotherapy lasted for 6 months
Exclusion Criteria
- •Severe Osteoarthritis (grade 4 candidates for joint replacement surgery)
- •Rheumatic disease Clearly
- •Visible deformity of the knee Ankylosis
- •Contraindications to Ozone include: Hyperthyroidism , Thrombocytopenia ,Pregnancy , Recent heart attack history ,G6PD Deficiency
- •Definitive and partial Contraindications to Steroid injection include: Bacteremia, Sepsis, Intra articular or pre uricular infection, History of post injection Allergy, Intra articular or Osteochondral fracture at the injection site, Severe Joint destruction in Injection site , Artificial joint , Uncontrolled Coagulation disorders Specific skin lesion at the injection site
Investigators
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