Lung Ultrasound Score and Weaning Outcome

Not Applicable

Completed

• Conditions: Acute Respiratory Failure; Lung Ultrasound Score
• Interventions: Other: lung ultrasound

• Registration Number: NCT05289960
• Lead Sponsor: Cairo University

Brief Summary

Objectives: Failure of extubation of patients on mechanical ventilation is one of the common problems in the ICU.

Aim of work: To evaluate the validity of lung ultrasound score in prediction of weaning outcomes and post-extubation distress.

Detailed Description

Methods: A prospective observational study of 50 patients planned for extubation who passed a spontaneous breathing trial, lung ultrasound score and serum level of NT-PRO BNP were done to all patients at end of spontaneous breathing trial, and all patients were followed after extubation and monitored for oxygenation, re-intubation rate, ICU stay, and ICU mortality.

Study Timeline

• Study Start: 2020-12-01
• Primary Completion: 2022-02-28
• Status Verified: 2022-03
• Study Completion: 2022-03-01
• Study First Submitted: 2022-03-02
• Study First Submitted QC: 2022-03-11
• Last Update Submitted: 2022-03-21
• Study First Posted: 2022-03-22
• Last Update Posted: 2022-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1. Patients age > 18 years

2. Patients intubated and mechanically ventilated for more than 48 hours in the intensive care unit and planned for extubation.

Exclusion Criteria

• 1. Patients < or =18 years 2. Patients with left ventricular failure

  2. Right ventricular failure

  3. Pulmonary hypertension

  4. Aortic valve disease

  5. Hyperthyroidism

  6. Tracheostomy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients eligible for weaning by spontaneous breathing trial	lung ultrasound	-
non invasive ventilation after weaning	lung ultrasound	-

Primary Outcome Measures

Name	Time	Method
Extubation success	48 hours	number of participants that do not need for respiratory support neither NIV nor intubation for one week during ICU stay

Trial Locations

Locations (1)

Cairo University Hospitals; 🇪🇬 Cairo, Egypt