The Effect of Oxygen Concentration During Alveolar Recruitment on Absorption Atelectasis

Seoul National University Hospital1 site in 1 country98 target enrollmentMay 15, 2019

ConditionsAtelectasis, Postoperative Pulmonary

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Atelectasis, Postoperative Pulmonary
Sponsor: Seoul National University Hospital
Enrollment: 98
Locations: 1
Primary Endpoint: Modified lung ultrasound score
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate the effect of oxygen concentration during alveolar recruitment on absorption ateletasis.

Registry

clinicaltrials.gov

Start Date

May 15, 2019

End Date

July 10, 2020

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Seoul National University Hospital

Responsible Party

Principal Investigator

Jae-Hyon Bahk, MD, PhD

Professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

•Patients undergoing laparoscopic obstetric or colon surgery with Trendelenburg position

Exclusion Criteria

•American Society of Anesthesiologists physical status IV or more
•Severe cardiovascular disease
•Severe chronic obstructive pulmonary disease, emphysema
•History of pneumothorax, bullae
•History of lung resection surgery
•Conversion to laparotomy
•Refusal to participate

Outcomes

Primary Outcomes

Modified lung ultrasound score

Time Frame: Intraoperative (at the end of operation, before emergence)

The score is calculated by adding up the 12 individual quadrant scores assessed using lung ultrasound. Each quadrant score ranges from 0 (minimal atelectasis)\~3 (severe atelectasis), so the maximum total score is 36.

Secondary Outcomes

Modified lung ultrasound score(Postoperative 30 minutes)
Intraoperative desaturation(Intraoperative)
Intraoperative partial pressure of arterial oxygen/fraction of inspired oxygen ratio(Intraoperative (20minutes after each recruitment))
Postoperative partial pressure of arterial oxygen/fraction of inspired oxygen ratio(Postoperative 30 minutes)
Postoperative pulmonary complication(Postoperative 24 hours)