Australian Lung Screen Trial for Aboriginal and Torres Strait Islander Peoples

Not Applicable

• Conditions: Cancer; Cancer - Lung - Non small cell; Cancer - Lung - Small cell; Public Health - Health service research

• Registration Number: ACTRN12624000586516
• Lead Sponsor: The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-08
• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

Aboriginal and Torres Strait Islander people who are generally fit and well
Aboriginal and Torres Strait Islander people aged 50 to 80 years who have a 20 pack-year smoking history and currently smoke or quit within the past 15 years (2021 US Preventative Services Task Force (USPSTF) criteria).
Aboriginal and Torres Strait Islander people aged 50 to 70 years who have a history of cigarette smoking of at least 30 pack years, and, if former smokers, quit within the previous 10 years (Medical Services Advisory Committee (MSAC) criteria).
Aboriginal and Torres Strait Islander people assessed as having a PLCOm2012 lung cancer risk score assessment of more than 1.5 percent over 6 years.

Exclusion Criteria

Clinical symptoms suspicious for lung cancer e.g., haemoptysis, chest pain, weight loss.
Any medical condition, such as severe heart disease (e.g., unstable angina, chronic congestive heart failure), acute or chronic respiratory failure, home oxygen
therapy, bleeding disorder, that in the opinion of the investigator could jeopardize the subject’s safety during participation in the study or unlikely to benefit from
screening due to shortened life-expectancy from the co-morbidities.
Have been previously diagnosed with lung cancer.
Have had other non-curatively treated cancer outside the lung.
Pregnancy
Pneumonia or bronchitis requiring antibiotic treatment within the last 12 weeks.
Unwilling to have a spiral chest CT.
Chest CT within 2 years
Does not fit into CT scanner table.
Cannot lie on CT scanning table on the back with arms over the head.
Received chemotherapy or cytotoxic drugs within the last 6 months.
Unwilling to sign a consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified