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Clinical Trials/NCT03274674
NCT03274674
Completed
Not Applicable

New Approach to Increasing Gingival Thickness in Individuals With Fine Gingival Phenotype:Injectable Platelet Rich Fibrin (I-PRF)

Bezmialem Vakif University1 site in 1 country29 target enrollmentApril 4, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periodontoclasia
Sponsor
Bezmialem Vakif University
Enrollment
29
Locations
1
Primary Endpoint
Gingival thickness (mm)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival thickness without the need for surgical procedures

Detailed Description

Due to the thin gingival phenotype, gingival recession is a problem. The investigators aimed to increase the gingival thickness using i-PRF with microneedle without considering surgical procedures, considering the positive effects of platelet concentrations on revascularization and wound healing in individuals with bone defect, fenestration and gingival thickness which are prone to gingival recession .

Registry
clinicaltrials.gov
Start Date
April 4, 2017
End Date
June 1, 2018
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Never smokers
  • Had no history of systemic disease
  • Aged ≥18 years old

Exclusion Criteria

  • Patients with a history of diabetes mellitus or systemic disease
  • Patients who were under any medication that was known to influence periodontal tissues
  • Patients with hormonal changes such as pregnancy or lactation
  • Toothless individuals
  • Patients who were clotting disorders

Outcomes

Primary Outcomes

Gingival thickness (mm)

Time Frame: 2 months

Change in clinical measures of gingival thickness

Secondary Outcomes

  • Bleeding on probing (BOP)(2 months)
  • Plaque Index (PI)(2 months)
  • Gingival Index (GI)(2 months)
  • Clinical attachment level (CAL)(2 months)
  • Probing pocket depth (PD)(2 months)

Study Sites (1)

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