Vellus Hair Loss as a Marker for Peri-ocular Malignancy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- NHS Lothian
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Vellus hair presence/absence
研究概览
简要总结
Skin cancers around the eye are common, but so are other lid lumps. It is useful to be able to tell which lumps are likely to be cancer.
This study looks at whether the loss of fine hairs (vellus hairs) on the skin are a good indicator of whether a lump is a skin cancer or not.
The investigators are recruiting patients who have lid lumps who haven't had a biopsy before, who would be having a biopsy as part of their treatment, and seeing whether those who have loss of the fine skin hairs are the same as those who have skin cancer confirmed on their biopsy.
The study doesn't involve any extra examinations or treatments for participants. The investigators look at the patients before the biopsy as part of their usual care, and take a note of whether or not they have lost the fine hairs at this stage.
The main benefit of participating is that the medical community has better evidence about which lid lumps are likely to represent skin cancer, helping future diagnosis.
There are no additional risks to participating. The risks of biopsy are unchanged whether patients participate in the study or not.
The study is run from the Princess Alexandra Eye Pavilion in Edinburgh.
The investigators aim to start the study in Spring 2020, and will most likely recruit for 6 months depending on the number of participants recruited.
There is no additional funding from any source at present - the work will be undertaken by doctors in their research time.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing biopsy for peri-ocular lesion
排除标准
- •Age under 18; previous biopsy or excision on the same lid
研究组 & 干预措施
Patients undergoing biopsy
Patients undergoing biopsy (incisional or excisional) of peri-ocular lesions. Pre-operative examination for presence or absence of vellus hairs
干预措施: Examination for presence or absence of vellus hairs (Diagnostic Test)
结局指标
主要结局
Vellus hair presence/absence
时间窗: Day 1
Examination for the presence or absence of vellus hairs prior to biopsy
Biopsy result
时间窗: On receipt of biopsy result from pathology lab (~1 week)
Biopsy result looking for malignancy
次要结局
未报告次要终点
