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Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain

Phase 3
Completed
Conditions
Diabetic Neuropathies
Osteoarthritis
Low Back Pain
Migraine
Registration Number
NCT00228605
Lead Sponsor
Cephalon
Brief Summary

The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
500
Inclusion Criteria
  • Chronic pain diagnosis
  • Opioid tolerant
  • Has on average 1-4 breakthrough pain episodes per day
Exclusion Criteria
  • Drug abuse history
  • Cardiopulmonary disease
  • Monoamine oxidase inhibitors (MAOIs)
  • Expected to have surgery to relieve the pain

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Safety and tolerability when used over a 12-month period for the management of breakthrough pain in opioid tolerant patients
Secondary Outcome Measures
NameTimeMethod
Assess the patients' quality of life through questionnaires
Assess the patients' overall medication preferences
Assess the patients' overall medication performance

Trial Locations

Locations (36)

MedSearch

🇺🇸

Calera, Alabama, United States

Clinical Research Consultants, Inc.

🇺🇸

Hoover, Alabama, United States

Arizona Research Center

🇺🇸

Phoenix, Arizona, United States

NEA Clinic

🇺🇸

Jonesboro, Arkansas, United States

Lynn Institute of the Rockies

🇺🇸

Colorado Springs, Colorado, United States

Radiant Research-Daytona Beach

🇺🇸

Daytona Beach, Florida, United States

Advent Clinical Research Centers, Inc.

🇺🇸

Atlanta, Georgia, United States

Gold Coast Research

🇺🇸

Weston, Florida, United States

Center for Prospective Outcome Studies, Inc.

🇺🇸

Marietta, Georgia, United States

North Fulton Regional Hospital Pain Center

🇺🇸

Roswell, Georgia, United States

Scroll for more (26 remaining)
MedSearch
🇺🇸Calera, Alabama, United States

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