Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study

Not Applicable

Completed

• Conditions: Fluid Overload
• Interventions: Other: General anesthsia; Other: oxytocin and spinal anesthesia

• Registration Number: NCT04328870
• Lead Sponsor: University of Jordan

Brief Summary

To determine if combining intravenous oxytocin infusion and spinal anesthesia will reduce the amount of glycine absorption in patients undergoing operative hysteroscopy

Detailed Description

Prospective controlled study in premenopausal patients who had hysteroscopic surgery including endometrial resection, endometrial polypectomy, myomectomy resection and uterine septal resection. The effect of combined spinal anesthetic with oxytocin infusion on fluid deficit was studied.

Study Timeline

• Study Start: 2018-05-20
• Primary Completion: 2019-09-30
• Study Completion: 2019-09-30
• Status Verified: 2020-03
• Study First Submitted: 2020-03-25
• Study First Submitted QC: 2020-03-30
• Last Update Submitted: 2020-03-30
• Study First Posted: 2020-03-31
• Last Update Posted: 2020-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 88

Inclusion Criteria

• premenopausal with no cardiovascular comorbidities

Exclusion Criteria

• endometrial cancer cases, patients who received pre-operative hormonal preparations, previously resected cases and cases done using bipolar diathermy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
general anesthsia	General anesthsia	general anesthesia alone
oxytocin and spinal anesthesia	oxytocin and spinal anesthesia	spinal anesthesia combined with intravenous oxytocin infusion

Primary Outcome Measures

Name	Time	Method
fluid overload	16 months	Fluid (glycine) excessive absorption into the patient

Trial Locations

Locations (1)

University of Jordan; 🇯🇴 Amman, Jordan