Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain in Patients Undergoing Uniport Thoracoscopic Pulmonary Resection
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pain-associated inflammatory factor
研究概览
简要总结
Lung cancer is the leading cause of cancer-related death worldwide. Thoracoscopic pulmonary resection is a prevalent management for early stage of lung cancer. Placement of chest tube is the standard procedure after surgery, which causes pain that cannot be ignored. The investigators aimed to determine whether a muscle layer fixation of thoracic drainage tube could release postoperative pain in patients with uniport thoracoscopic pulmonary resection compared with conventional skin fixation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •* 18\50% and ejection fraction (EF) \>50%of predicted value\]. Resting blood gas analysis showing arterial partial pressure of oxygen (PaO2)≥75 mmHg and arterial partial pressure of carbon dioxide (PaCO2) \<45 mmHg;
排除标准
- •History of ipsilateral surgery and other conditions which can result in extensive pleural adhesion;
- •Coagulopathy, hypoxemia (PaO2 <60 mmHg), hypercapnia [arterial carbon dioxide tension(PaCO2) >50 mmHg];
- •Significant cardiac history.
结局指标
主要结局
Pain-associated inflammatory factor
时间窗: the first day after surgery
the level of pain-associated inflammatory factor in blood, including CRP, PCT, IL6 and TNFa
Postoperative Pain
时间窗: From date of operation until the date of chest tube removal, assessed up to 7 days
The postoperative pain is assessed using a Visual Analog Scale (VAS)
Dosage of analgesics
时间窗: From date of operation until the date of chest tube removal, assessed up to 7 days
Dosage of analgesics
次要结局
未报告次要终点
研究者
Kun Li, MD
Kun Li, MD
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University