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Clinical Trials/NCT00893126
NCT00893126
Completed
Not Applicable

Premature Coronary Artery Disease (CAD) in Severe Psoriasis

University of Michigan1 site in 1 country46 target enrollmentNovember 2009
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ConditionsPsoriasisCoronary Artery Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psoriasis
Sponsor
University of Michigan
Enrollment
46
Locations
1
Primary Endpoint
To establish the relationship between psoriasis and coronary disease
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to compare the prevalence and severity of CAD (coronary artery disease) in patients with and without severe psoriasis, otherwise matched for cardiovascular risk factors.

Detailed Description

To establish the relationship between psoriasis and coronary disease by comparing the prevalence and severity of CAD (coronary artery disease) in patients with and without severe psoriasis, otherwise matched for cardiovascular risk factors, as determined by CT coronary calcium scoring and Coronary CT angiography.

Registry
clinicaltrials.gov
Start Date
November 2009
End Date
August 2016
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Prachi P Agarwal, M.D.

Principal Investigator

University of Michigan

Eligibility Criteria

Inclusion Criteria

  • •Patients with severe psoriasis as determined by more than two episodes of systemic or inpatient treatment and 10% or more body surface area involvement.
  • •Male or female ages 18 to 55 (because CAD risk has been shown to be greatest in younger psoriasis patients in earlier studies, this pilot study will focus on young individuals).
  • •Able to give informed consent

Exclusion Criteria

  • •Prior diagnosis of CAD (coronary artery disease) or heart disease based upon one or more of the following:
  • •coronary arteriography
  • •percutaneous coronary intervention
  • •cardiac surgery including bypass graft surgery
  • •valve surgery
  • •congenital heart disease repair
  • •stress ECG or imaging
  • •myocardial infarction
  • •angina or unstable angina
  • •congestive heart failure

Outcomes

Primary Outcomes

To establish the relationship between psoriasis and coronary disease

Time Frame: 1 year

Study Sites (1)

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