Evolution of diaphragm function during spontaneous breathing trials

Not Applicable

Completed

• Conditions: - Mechanically ventilated patients; Mechanical ventilation; Spontaneous breathing trials; Diaphragm function; Rapid shallow breathing index

• Registration Number: TCTR20160808001
• Lead Sponsor: Faculty of Medicine Siriraj Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-08
• Study Completion: 2017-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Age >/= 18 years old
2. Ready to be wean as follows
- FiO2 - Positive end expiratory pressure - PaO2/FiO2 > 200
- Respiratory rate < 30/min
- Stable hemodynamic
- Conscious and cooperative
3. Willing to participate the study

Exclusion Criteria

1. Known case of diaphragm paralysis
2. Underlying neuromuscular disorder
3. Alteration of consciousness with Glasgow Coma Scale </= 8

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Thickening fraction of the diaphragm during SBTs 0, 5, 10, 15, 30, 60 minutes Diaphragm ultrasound

Secondary Outcome Measures

Name	Time	Method
Thickening fraction of the diaphragm between patients who success and fail SBTs 0, 5, 10, 15, 30, 60 minutes Diaphragm ultrasound,Rapid shallow breathing index between patients who success and fail SBTs 0, 5, 10, 15, 30, 60 minutes respiratory rate over average tidal volume,Day of mechanical ventilation At the end of ICU admission N/A