JPRN-UMIN000021146
Recruiting
Phase 1
Phase I study of optimal dose and pharmacokinetics of a Uracil/Tegafur (UFT) plus oral leucovorin regimen after liver resection for colorectal liver metastasis - Phase I study of optimal dose and pharmacokinetics of a Uracil/Tegafur (UFT) plus oral leucovorin regimen after liver resection for colorectal liver metastasis
Oita university, faculty of medicine, department gastroenterology and pediatric surgery0 sites18 target enrollmentFebruary 22, 2016
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- iver resection for liver metastasis of colorectal cancer
- Sponsor
- Oita university, faculty of medicine, department gastroenterology and pediatric surgery
- Enrollment
- 18
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\.Active synchronous or metachronous malignancy other than carcinoma in situ 2\.Serious postoperative complications 3\.Serious coexisting illness A) Uncontrolled diabetes mellitus B) Uncontrolled hypertension C) History of myocardial infarction, unstable angina within 6 months prior to the registration D) Severe pulmonary dysfunction E) Liver cirrhosis 4\.Ascites or pleural effusion needed to 5\.Positive HBs antigen 6\.Bleeding, paralysis, obstruction or ulcer of gastrointestinal tract 7\.Pregnant or nursing 8\.Severe mental disorders 9\.Not suitable for participating in the study for any other Reason by the physician
Outcomes
Primary Outcomes
Not specified
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