A comparative study of blood removal therapy followed by bharangi extract nebulization and bharangi extract nebulization in bronchial asthma

Phase 1/2

Not yet recruiting

• Conditions: Moderate persistent asthma. Ayurveda Condition: TAMAKASVASAH,

• Registration Number: CTRI/2021/11/037807
• Lead Sponsor: Sri Dharmasthala Manjunatheshwara College Of Ayurveda and Hospital Hassan

Brief Summary

This study is an open label, double arm randomized prospective clinical trial to evaluate the combined effect of siravyadha followed by bharangi arka nebulization with the standard group bharangi arka nebulization in Tamaka Shwasa( Bronchial Asthma) that will be conducted in India.

Primary outcome measures will be laghava, vedana shanti, vyadhirvega kshaya, mana prasada and secondary outcome measures will be assessed on the basis of relief in the signs and symptoms of Tamaka Shwasa, which will be assigned suitable scores(GINA) Time points will be before treatment, immediately after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in the subjects of group A.

While in group B, primary and secondary measure will be assessed before treatment, 15 minutes after nebulization.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-08-23
• Study Start: 2021-12-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Mild and moderate grade of Bronchial Asthma as per GINA 2.
• Subjects with Hb more than 10 gm percent 3.
• Subjects with normal clotting and bleeding time.

Exclusion Criteria

• Subjects who are known case of Tuberculosis Emphysema COPD 2.
• Subjects who are known case of Cardiac Diseases 3.
• Subjects who are known case of HIV and HBsAg 4.
• Subjects with uncontrolled Diabetes Mellitus and Hypertension.
• Subjects with Bleeding Disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Samyak siravyadha lakshanas will be observed:	Measures will be assessed by giving proper gradings before treatment, after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in subjects of Group A | In Group B, measures will be assessed before treatment and 15 minutes after nebulization
1. Laghava	Measures will be assessed by giving proper gradings before treatment, after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in subjects of Group A | In Group B, measures will be assessed before treatment and 15 minutes after nebulization
2. Vedana shanti	Measures will be assessed by giving proper gradings before treatment, after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in subjects of Group A | In Group B, measures will be assessed before treatment and 15 minutes after nebulization
3. Vyadhirvega kshaya	Measures will be assessed by giving proper gradings before treatment, after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in subjects of Group A | In Group B, measures will be assessed before treatment and 15 minutes after nebulization
4. Mana prasada	Measures will be assessed by giving proper gradings before treatment, after siravyadha, 15 minutes after siravyadha, before nebulization, 15 minutes after nebulization in subjects of Group A | In Group B, measures will be assessed before treatment and 15 minutes after nebulization

Secondary Outcome Measures

Name	Time	Method
The effect of the therapy will be assessed on the basis of relief of following signs and symptoms of Tamaka Shwasa which will be assigned suitable scores(GINA scale):	1. Gurukuraka

Trial Locations

Locations (1)

In patient Department of panchakarma; 🇮🇳 Hassan, KARNATAKA, India

In patient Department of panchakarma

🇮🇳Hassan, KARNATAKA, India

DrMonika

Principal investigator

9416842630

pg19147@sdmcahhassan.org