NCT00295776终止2 期
Lamictal in the Treatment of Post-Herpetic Neuralgia-A Safety, Efficacy,Randomized, Double Blind, Placebo Controlled, Cross-Over Study
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 试验地点
- 2
研究概览
简要总结
To assess the efficacy of Lamictal for the treatment of pain and reduction of allodynia in patients with post herpetic neuralgia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients will be over the age of 18,
- •Need to have a diagnosis of Post-Herpetic Neuralgia,
- •Minimum of 4 on the Likert Pain Scale,
- •If currently taking TCA and/or Gabapentin, need to have been on stable dose for minimum of 4 weeks
排除标准
- •Currently on any antiepileptic drugs (AED), except for Gabapentin.
- •Currently taking opioid or unwilling to washout prior to the study,
- •Pregnant and lactating,
- •Have active severe systemic disease,
- •History of Stevens-Johnson syndrome or TEN,
- •Clinically significant abnormal lab values,
- •Known drug allergy to Lamictal,
- •Patients on Fibrates (Tricor and Lopid),
- •History of major psychiatric disturbance and substance abuse.
- •Valproate due to increase chances of severe rash,
- •Lidocaine Patch,
- •Use of hormonal contraceptives (birth control pills, patch, ring, injection)
研究者
研究点 (2)
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