Assessment of PFM Strength and Function After Radiotherapy Treatment in Women with Pelvic Cancers
Completed
- Conditions
- Pelvic Muscle Strength and Function
- Registration Number
- NCT06820801
- Lead Sponsor
- Cairo University
- Brief Summary
Assessment the effect of radiotherapy treatment on pelvic floor muscles in women with pelvic cancers
- Detailed Description
Evaluate the impact of radiotherapy treament on pelvic floor muscles strength and function in women with cervical and rectal cancers
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
- women between 30 -50 years old
- diagnosed with cervix or rectal cancers
- married
- will be treated with preoperative radiotherapy for at least 5 weeks
- had not any pelvic operations in the past
Exclusion Criteria
- un married women
- Age below 30 or above 50 years old
- has another type of pelvic tumors
- has any metastasis
- had any pelvic surgeries
- will be treated with short course radiotherapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PFM strength and function 3 months Pelvic floor muscles strength and function
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways mediate radiation-induced pelvic floor muscle atrophy in cervical and rectal cancers?
How does intensity-modulated radiation therapy (IMRT) compare to standard radiotherapy in preserving pelvic floor function post-treatment?
Which biomarkers correlate with radiation-induced pelvic floor dysfunction in gynecological and colorectal cancer patients?
What are the long-term adverse events of pelvic floor muscle weakness after radiotherapy for cervical and rectal malignancies?
Are there adjunct therapies like anti-inflammatory agents or muscle regeneration protocols to mitigate radiation damage in pelvic floor muscles?
Trial Locations
- Locations (1)
Elahrar oncology center and zagazeg university oncology center
🇪🇬Zagazeg, Alsharkia, Egypt