Hypertonic Saline in Acute Bronchiolitis: a Randomised controlled trial and Economic evaluation

Sheffield Children's NHS Foundation Trust (UK)0 sites300 target enrollmentMay 23, 2011

Overview

Registry

who.int

Start Date

May 23, 2011

End Date

April 30, 2012

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

Sheffield Children's NHS Foundation Trust (UK)

•Previously healthy infants under 1 year of age admitted to hospital with a clinical diagnosis of acute bronchiolitis, following the UK definition.

•1\. Wheezy bronchitis or asthma ? children with an apparent viral respiratory infection and wheeze with no or occasional crepitations
•2\. Previous lower respiratory tract infections
•3\. Risk factors for severe disease (gestation \< 32 weeks, immunodeficiency, neurological and cardiac conditions)
•4\. Participation in another study involving investigational medication
•5\. Subjects where the carer?s English is not fluent and translational services are not available
•6\. Requiring admission to high dependency or intensive care units at the time of recruitment