MedPath

Effects of Terminalia Chebula on hemorrhoids

Phase 3
Recruiting
Conditions
hemorrhoids.
internal hemorrhoids without complications
Registration Number
IRCT2016101830372N1
Lead Sponsor
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
80
Inclusion Criteria

Inclusion criteria include 18 to 65 year-old women and men who have grade I and II hemorrhoids. Exclusion criteria include every severe disease; presence of cancer in every part of the body; every disease in anorectal except hemorrhoids; pregnant and lactating women; patients with history of using anticoagulant, antiplatelet drugs, steroids drugs, drugs with flavonoids (less than a month ago) and pain killers (less than a week ago).

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Bleeding of hemorrhoids. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: The number of days (questionnaire).;Pain. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: Visual Analog Scale (VAS) (questionnaire).;The size of pilel mass. Timepoint: Before the intervention, and at the end of the intervention. Method of measurement: Rectosigmoidoscopy.;Constipation. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: ROM III criteria (questionnaire).;Exercise. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: At least half an hour daily for 4 days a week (questionnaire).
Secondary Outcome Measures
NameTimeMethod
Headache. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: Visual Analog Scale (VAS) (questionnaire).;Vertigo. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: Grading of vertigo severity (questionnaire).;Diarrhea. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: Mild: <3 loose stools per day, Moderate: 3 to 10 per day, Severe: >10 per day (questionnaire).;Dry skin. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: skin dry grading scale (questionnaire).;Constipation. Timepoint: Before and after the intervention, at the end of every week, for four weeks. Method of measurement: ROM III criteria (questionnaire).
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