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临床试验/NCT06782828
NCT06782828尚未招募不适用

Accuracy of FNAC in Diagnosis of Thyroid Nodules

Assiut University0 个研究点目标入组 100 人开始时间: 2025年3月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
Incidence of true positive results of FNAC after thyroidectomy

研究概览

简要总结

Detection of degree of accuracy of FNAC in diagnosis of thyroid nodules

详细描述

Accuracy in diagnosis in any case is required, and this is beneficial to the patient and the physician, and with the development that currently exists and the trend to use less invasive techniques, accuracy of FNAC should be studied well.1.Thyroid nodules are common and the principal method of diagnosis is fine-needle aspiration cytology (FNAC).2. Can investigators depend on FNAC alone in diagnosis of thyroid nodule in the future?!3. In this study, investigators will compare the results of (FNAC) versus (Biopsy) in diagnosis of thyroid nodule in AUH , to detect the degree of accuracy of FNAC.4. FNAC is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules.5. Background Routine application of fine needle aspiration cytology (FNAC) has decreased unnecessary referral of thyroid nodules for surgical treatment and has also increased the cancer rates found in surgery materials. Success of thyroid FNAC depends on skilled aspiration, skilled cytological interpretation and rational analysis of cytological and clinical data. The aim of this study was to determine the diagnostic accuracy rates of thyroid FNAC results obtained in our hospital.6. The FNAC is a sensitive, specific, and accurate initial diagnostic test for the preoperative evaluation of patients with thyroid swellings in our setting as well. The correlation of cytological and histopathological diagnoses is an important quality assurance method, as it allows cytopathologists to calculate their false-positive and false negative results.7

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
10 Years 至 80 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • thyroid disease
  • multinodular
  • single nodule
  • TIRAD 3 or more by US
  • thyroid disease underwent FNAC then surgery
  • all age groups
  • patient fit for surgery

排除标准

  • patients with comorbidities.
  • patients unfit for surgery
  • patients who refused surgery.
  • Patient with no diagnostic FNAC.

结局指标

主要结局

Incidence of true positive results of FNAC after thyroidectomy

时间窗: 12 days

Accuracy of FNAC in thyroid nodules compared to surgical specimen histopathological examination

Percentage of malignant thyroid nodules not observed by FNAC

时间窗: 12 days

Percentage of malignant thyroid nodules that FNAC fails to detect

Incidence of false negative results by FNAC

时间窗: 12 days

False negative that diagnosed by FNAC not malignant but proved malignancy after surgical excision

Percentage of total number of true results of FNAC to the total number of cases

时间窗: 12 days

Accuracy of FNAC

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mostafa Abed Abdulmoneim Mohammed

Principal Investigator

Assiut University

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