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Evaluation of the Therapeutic effect of soothing the liver and regulating mind Integrated Rehabilitation Program on Post-Stroke Depression based on salivary Transcriptome

Early Phase 1
Conditions
Post-Stroke Depression
Registration Number
ITMCTR2024000128
Lead Sponsor
The First Affiliated Hospital of Henan University of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1 the age was 18-85 years old, 2 met the diagnostic criteria of stroke and depressive disorder, 317 Hamilton depression scale scores > 7, < 24, 4 patients who did not systematically take antidepressants, 5 signed informed consent and volunteered to participate in this study.

Exclusion Criteria

1)17 items of Hamilton Depression scale score = 7, = 24; 1) patients with obvious suicidal tendency assessed by specialists; 3) previously diagnosed with severe depressive disorder, cognitive impairment, schizophrenia, bipolar disorder, substance abuse or other mental disorders; 4) patients with severe dysfunction after stroke, or with serious heart, liver, kidney and other medical diseases or tumors. 5)There were participants in acupuncture, traditional Chinese medicine and other related therapies in the past 3 months.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
HAMD-17;BDI-II;
Secondary Outcome Measures
NameTimeMethod
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