Assessment of High Flow Nasal Cannula Oxygenation in EBUS Bronchoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- drop in oxygen saturation during procedure
研究概览
简要总结
This study is a prospective randomised trial where a computer will randomly allocate
patients to one of two possible methods of delivering oxygen during the procedure of
bronchoscopy. This trial compares high flow nasal cannula (HFNC) with nasal prongs in
delivering oxygen to patients undergoing endo-bronchial ultrasound guided trans-
bronchial nodal aspiration (EBUS-TBNA) a specialised form of bronchoscopy procedure.
HFNC uses humidified higher gas flow rates than conventional low flow systems such as
nasal prongs which are limited by the respiratory rate and effort.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with a peripheral arterial pulse oximetry ≥ 90% breathing room air
- •Age ≥ 18 years
- •Able to breathe spontaneously throughout the procedure
排除标准
- •Respiratory or cardiac failure
- •Recent myocardial infarction < 6 weeks ago
- •On long term oxygen therapy, those with tracheostomy and/ or non-invasive or invasive mechanical ventilation
- •Nasal and/ or nasopharyngeal disease
- •Inability to give informed consent
- •Hepatic or end stage renal disease
- •Pregnancy
结局指标
主要结局
drop in oxygen saturation during procedure
时间窗: through procedure completion defined as withdrawing scope from patient's mouth, an average of 30 minutes
the difference in oxygen saturation levels between pre-treatment assessments and the lowest saturation level achieved during treatment
次要结局
- change in venous CO2(1 hour after procedure)
- end tidal CO2 during procedure(through procedure completion defined as withdrawing scope from patient's mouth an average of 30 minutes)
- Patient experience measure on a visual analogue scale(up to 3 hours after procedure)
- endotracheal intubation during or post procedure(24 hours)
研究者
Mohammed Ahmed
Specialist Registrar in Respiratory Medicine
University College Hospital Galway