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Examination of the efficacy of dapagliflozin in patients with type 2 diabetes

Not Applicable
Recruiting
Conditions
Type 2 diabetes
Registration Number
JPRN-UMIN000021954
Lead Sponsor
Tonami general hospital Department of diabetes mellitus and endocrinology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

Not provided

Exclusion Criteria

1.Patients with hypersensitivity to an ingredient of dapagliflozin 2.Diabetic ketoacidosis 3.Past history of coma or severe hypoglycemia 4.Severe infection or serious trauma 5.Severe liver injury, renal failure, cardiac disease, proliferative retinopathy 6.Past history of cerebral infarction 7.Past history of malignant tumor 8.Women with during pregnancy, nursing, or pregnant likelihood 9.Inadequate patients judged by doctor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fasting plasma glucose and HbA1c after administration 1, 3, 6, 9, 12, 18, 24, 36 months later, every 12 months thereafter if possible.
Secondary Outcome Measures
NameTimeMethod
Change of body weight, blood pressure, kidney and liver function, lipid profile, and blood dapagliflozin concentrations after administration 1, 3, 6, 9, 12, 18, 24, 36 months later, every 12 months thereafter if possible. Blood dapagliflozin concentrations is measured until 36 months. Adverse event. Kidney function is urinary albumin, L-FABP and eGFR etc.
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