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CLARITY Imaging Study

Not Applicable
Conditions
Glaucoma
Interventions
Other: sodium hyaluronate eyedrops
Registration Number
NCT03758859
Lead Sponsor
Imperial College London
Brief Summary

OCT image quality is necessary to provide accurate diagnostic information to ophthalmologists. The increasing resolution of imaging techniques will require ever more high standards of optical transmission through the cornea and tear film. Given that lubricant drops can improve optical transmission through the cornea, this study will attempt to quantify this. The primary objective is to assess the effect of cross-linked sodium hyaluronate on OCT image quality compared to the effect of blinking alone.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Patients subjectively deemed to have poor image quality by the photographer
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Exclusion Criteria
  • Patients with a known adverse reaction to any of the constituents of the XLHA
  • Patients wearing contact lenses
  • Patients who have used eyedrops in the past 2 hours
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
sodium hyaluronate eye dropssodium hyaluronate eyedropsthe randomly allocated eye will receive sodium hyaluronate drops, followed by a repeat OCT scan; images are then evaluated for clarity by the masked assessor.
Primary Outcome Measures
NameTimeMethod
Clarity of retinal images obtained by Optical Coherence Tomography.immediately after the administration of drops.

Signal strength of OCT scan

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Western Eye Hospital

🇬🇧

London, United Kingdom

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