CLARITY Imaging Study: The Effect Of Cross-linked Sodium Hyaluronate On The Quality Of Optical Coherence Tomography Imaging
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Clarity of retinal images obtained by Optical Coherence Tomography.
研究概览
简要总结
OCT image quality is necessary to provide accurate diagnostic information to ophthalmologists. The increasing resolution of imaging techniques will require ever more high standards of optical transmission through the cornea and tear film. Given that lubricant drops can improve optical transmission through the cornea, this study will attempt to quantify this. The primary objective is to assess the effect of cross-linked sodium hyaluronate on OCT image quality compared to the effect of blinking alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
盲法说明
Randomisation is between eyes i.e. eye exposed to blinking alone vs eye exposed to lubricant drops
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients subjectively deemed to have poor image quality by the photographer
排除标准
- •Patients with a known adverse reaction to any of the constituents of the XLHA
- •Patients wearing contact lenses
- •Patients who have used eyedrops in the past 2 hours
研究组 & 干预措施
sodium hyaluronate eye drops
the randomly allocated eye will receive sodium hyaluronate drops, followed by a repeat OCT scan; images are then evaluated for clarity by the masked assessor.
干预措施: sodium hyaluronate eyedrops (Other)
结局指标
主要结局
Clarity of retinal images obtained by Optical Coherence Tomography.
时间窗: immediately after the administration of drops.
Signal strength of OCT scan
次要结局
未报告次要终点