Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- In-hospital cardiac and renal events
研究概览
简要总结
This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes.
The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital.
Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •>= 18 years, male or female EF <40%
排除标准
- •EF>40% Pregnancy or breastfeeding
研究组 & 干预措施
Prehospital ARNI users
干预措施: Prehospital ARNI use (Other)
Non-Prehospital ARNI users
干预措施: No prehospital ARNI use (Other)
结局指标
主要结局
In-hospital cardiac and renal events
时间窗: 3 months
次要结局
- NYHA classification(3 months)
研究者
Mrwan Ayman Ahmed Eassa
MS Student, Clinical Pharmacy Department, Future University in Egypt
Future University in Egypt