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Clinical Trials/NCT02543554
NCT02543554
Completed
Not Applicable

The Effect of Lung Protective Ventilation Initiated in the Emergency Department on the Incidence of Pulmonary Complications and Clinical Outcomes

Washington University School of Medicine1 site in 1 country1,705 target enrollmentOctober 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Mechanical Ventilation
Sponsor
Washington University School of Medicine
Enrollment
1705
Locations
1
Primary Endpoint
Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Early mechanical ventilation, if delivered with injurious settings, can lead to pulmonary complications, such as acute respiratory distress syndrome (ARDS). Mechanical ventilation in the emergency department (ED) has been studied infrequently when compared to the intensive care unit; however, data suggests that ED-based mechanical ventilation has significant room for improvement and may also be a causative factor in ARDS incidence.

Detailed Description

This is a before-after study examining the impact of implementing lung protective ventilation in the emergency department.

Registry
clinicaltrials.gov
Start Date
October 2014
End Date
March 2016
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Brian Fuller

Associate Professor of Anesthesiology and Emergency Medicine

Washington University School of Medicine

Eligibility Criteria

Inclusion Criteria

  • mechanically ventilated via an endotracheal tube in the ED

Exclusion Criteria

  • death in the ED,
  • death or discontinuation of ventilation within 24 hours,
  • chronic mechanical ventilation,
  • ARDS while in the ED
  • transfer to another hospital.

Outcomes

Primary Outcomes

Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department

Time Frame: 7 days

Secondary Outcomes

  • Number of Patients That Die During the Hospitalization(Patients will be followed for the duration of hospital stay)

Study Sites (1)

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