Different extubation methods to prevent lung collapse in elderly patients after major abdominal surgeries.
Not Applicable
- Conditions
- Health Condition 1: K807- Calculus of gallbladder and bile duct without cholecystitisHealth Condition 2: E119- Type 2 diabetes mellitus without complicationsHealth Condition 3: K469- Unspecified abdominal hernia without obstruction or gangrene
- Registration Number
- CTRI/2022/04/042115
- Lead Sponsor
- All India Institue Of Medical Sciences Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All Patients more than equal to 60 years of age undergoing major abdominal surgery.
Exclusion Criteria
1.BMI > 30 kg/m2
2.Severe Cardiopulmonary diseases
3.Hemodynamic Instability
4.Cerebrovascular Diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of low Fio2 (0.4) with recruitment manoeuvre during extubation <br/ ><br>against high Fio2(1) with or without recruitment manoeuvre on postoperative atelectasis measured by using lung ultrasound scoring(luss-parameter 1 used for sample size calculation as well) and <br/ ><br>oxygenation measured using Pao2 (parameter 2)and pao2/fio2 ratio(parameter 3).Timepoint: Lung ultrasound score(luss) measured -30 minutes preoperatively, 30minutes postoperatively and 24 hours postoperatively. <br/ ><br>pao2 and pao2/fio2 ratio measured using arterial blood gas - preoperatively(baseline before induction), 10 minutes after induction, 30 minutes post extubation, 6 hours postoperatively.
- Secondary Outcome Measures
Name Time Method Incidence of postoperative pulmonary complications like- 1.Incidence of desaturation <br/ ><br>2.oxygen requirement <br/ ><br>3.pneumothorax <br/ ><br>4. post-operative pneumonia <br/ ><br>5.post-operative icu requirement.Timepoint: Within in 24 hours post-operatively.