Advanced lung ultrasound to differentiate pneumonia and atelectasis in ICU patient
Completed
- Conditions
- Pneumonia, Atelectasis
- Registration Number
- NL-OMON21456
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 118
Inclusion Criteria
Adult (18 years) patients admitted to the ICU with consolidation on chest X-ray
Exclusion Criteria
ARDS, pulmonary contusion, contact isolation, COVID-19
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity, Specificity, Positive/Negative Predictive Values, Positive/Negative Likelihoodratios for pneumonia (for ultrasound parameters alone and within a clinical prediction score/decision tree) assessed by lung ultrasound (flow measured by color doppler imaging and the dynamic air bronchogram). Pneumonia will be defined as the clinical diagnosis established by the treating physician when all clinical data necessary to establish a diagnosis are available (cq. CRP, leukocytes, Temperature, physical examination, Imaging summary (CXR or CT) and gram stain information). The timepoint for this diagnosis will be set at within 24 hours after the gramstain is available. The ultrasound will be performed within 24 hours of chest X-ray and the ultrasound diagnosis will be made directly at the bedside after completion of the ultrasound exam without delay.
- Secondary Outcome Measures
Name Time Method Comparison of clinical prediction score based on clinical and ultrasound parameters for pneumonia and correlation with PF-ratio expressed as Sensitivity, Specificity, Positive/Negative Predictive Values, Positive/Negative Likelhoodratios and ICC. The exact same timeline in regards to measurement methods and timepoints will be used as for the primary outcome.