NL-OMON39690
Completed
Not Applicable
Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial. - Antibiotic treatment alone for acute simple appendicitis in children
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Appendicitis
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 50
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\* Written Informed consent obtained
- •\* Age 7\-17 years
- •\* Radiologically confirmed simple appendicitis, defined as:
- •a. Clinical findings:
- •i. Unwell, but not generally ill
- •ii. Localized tenderness in the right iliac fossa region
- •iii. Normal/hyperactive bowel sounds
- •iv. No guarding
- •v. No mass palpable
- •b. Ultrasonography:
Exclusion Criteria
- •The following patients will be excluded from participating in this study:
- •1\. Patients with severe general illness at time of presentation:
- •a. Generalized peritonitis defined as:
- •Diffuse inflammation of the peritoneum with clinical signs consisting of increasing abdominal pain, generalized tenderness, diffuse abdominal rigidity, sinus tachycardia, signs of paralytic ileus
- •b. Severe sepsis or septic shock, as defined by the international paediatric sepsis consensus conference \[36]. See attachment 1\.
- •c. Signs of complex appendicitis;2\. Patients with serious associated conditions or malformations such as:
- •a. Congenital or acquired cardiac or pulmonary disease with significant hemodynamic consequences
- •b. Immunodeficiency
- •c. Malignancy
- •d. Homozygous sickle cell disease
Outcomes
Primary Outcomes
Not specified
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