NCT03003182
Unknown
Not Applicable
A Prospective Cohort Study of Nasopharyngeal Carcinoma to Establish Prognostic Models, to Discover Toxicity Associated Predictors and to Validate Randomized Trials in Clinical Practice
Sun Yat-sen University1 site in 1 country2,000 target enrollmentMay 10, 2017
ConditionsNasopharyngeal Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Nasopharyngeal Cancer
- Sponsor
- Sun Yat-sen University
- Enrollment
- 2000
- Locations
- 1
- Primary Endpoint
- overall survival
- Last Updated
- 8 years ago
Overview
Brief Summary
This prospective cohort study aims to establish prognostic models, to discover toxicity associated predictors and to validate randomized trials in clinical practice.
Investigators
Fang-Yun Xie
Prof.
Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •histological confirmed nasopharyngeal carcinoma;
- •scanned by magnetic resonance imaging from calvaria vertex to clavicles before treatment;
- •pretreatment Epstein-Barr virus deoxyribonucleic acid copy number is available;
- •irradiated with intensity-modulated radiotherapy;
Exclusion Criteria
- •finishing anticancer therapy in two or more hospitals;
- •pregnancy or lactation;
- •diagnosed with other sort of cancer before or during the treatment.
Outcomes
Primary Outcomes
overall survival
Time Frame: 3-years
Secondary Outcomes
- Number of participants with treatment-related acute adverse events as assessed by CTCAE v4.0(30-days)
Study Sites (1)
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