A Study of Nasopharyngeal Carcinoma From Guangdong
- Conditions
- Nasopharyngeal Cancer
- Registration Number
- NCT03003182
- Lead Sponsor
- Sun Yat-sen University
- Brief Summary
This prospective cohort study aims to establish prognostic models, to discover toxicity associated predictors and to validate randomized trials in clinical practice.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
- histological confirmed nasopharyngeal carcinoma;
- scanned by magnetic resonance imaging from calvaria vertex to clavicles before treatment;
- pretreatment Epstein-Barr virus deoxyribonucleic acid copy number is available;
- irradiated with intensity-modulated radiotherapy;
Exclusion Criteria
- finishing anticancer therapy in two or more hospitals;
- pregnancy or lactation;
- diagnosed with other sort of cancer before or during the treatment.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method overall survival 3-years
- Secondary Outcome Measures
Name Time Method Number of participants with treatment-related acute adverse events as assessed by CTCAE v4.0 30-days
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What prognostic models were developed for nasopharyngeal carcinoma in the Sun Yat-sen University cohort study NCT03003182?
How do toxicity predictors from NCT03003182 compare to standard-of-care treatments for nasopharyngeal cancer?
What biomarkers are associated with response prediction in the Guangdong nasopharyngeal carcinoma study NCT03003182?
Are there molecular targets identified in NCT03003182 that could lead to new therapies for nasopharyngeal cancer?
What combination approaches have been validated in clinical practice for nasopharyngeal carcinoma based on NCT03003182 findings?
Trial Locations
- Locations (1)
Sun Yat-sen University Cancer Center
🇨🇳Guangzhou, Guangdong, China