BAD-DAPT Study

Not Applicable

Recruiting

• Conditions: Ischemic stroke; Branch atheromatous disease; D000083242

• Registration Number: JPRN-jRCT1041220038
• Lead Sponsor: Inoue Hiroyasu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-24
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

(1) Patients with lesions larger than 15 mm in diameter in the region of the lenticulostriate artery on diffusion-weighted MRI, and in the region of the pontine paramedian artery , where the infarcted lesion abuts the ventral side of the pons base, or whose infarction in the same region does not meet the above criteria but whose symptoms progress between onset and hospital visit.
(2) Patients who are hospitalized within 48 hours of onset
(3) Patients with hypertension, diabetes, dyslipidemia, chronic kidney disease, or history of cerebral infarction
(4) Patients aged 20 years or older on the date of enrollment
(5) Patients who have obtained written consent to participate in this study from the patient or the patient's surrogate.

Exclusion Criteria

(1) Patients taking antiplatelet drugs other than aspirin
(2) Patients with more than 50% stenotic lesion in the main artery branching the responsible vessel
(3) Patients with atrial fibrillation
(4) Patients who are bleeding or at high risk of bleeding
(hemophilia, intracranial hemorrhage, gastrointestinal bleeding, urinary tract bleeding, hemoptysis, vitreous hemorrhage, etc.)
(5) Patients taking oral anticoagulants
(6) Patients who used thrombolytic therapy (alteplase) for hyperacute stroke
(7) Patients with severe paralysis of the upper or lower limbs at the time of admission (corresponding NIHSS score of 4 = equivalent to MMT0)
(8) Patients with hypersensitivity to clopidogrel or prasugrel
(9) Patients who are unable to undergo MRI imaging due to non-MRI compatible pacemakers, other metal implants, claustrophobia, etc.
(10) Other patients deemed inappropriate as research subjects by the principal/assistant investigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified