Skip to main content
Clinical Trials/CTRI/2025/07/090098
CTRI/2025/07/090098
Not yet recruiting
Phase 3

Effectiveness of selected Ayurveda management protocol in adenoid hypertrophy among children of age group 5 to 10 years.

Dr. Musafar Ahammed1 site in 1 country23 target enrollmentStarted: August 4, 2025Last updated:

Overview

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Dr. Musafar Ahammed
Enrollment
23
Locations
1
Primary Endpoint
To assess the effect of Varanadi Kashaya, Kanchanara guggulu tablet, Vilwadi tablet

Overview

Brief Summary

Adenoid hypertrophy is a condition characterized by obstruction of airway in the

nasopharyngeal region by the enlarged adenoids. Adenoids gets

hypertrophied with/without acute or chronic infection of the adenoid, obstructing the posterior nasal

opening and respiratory, nasal and aural symptoms are shown. Even though the hypertrophy gets

atrophied during puberty, it can create serious difficulties to the individual in the form of upper airway

obstruction associated with, nasal block, mouth breathing, obstructive sleep apnea, hypopnea, and

upper airway resistance syndrome (UARS) etc. At present Adenoidectomy is the only definite

management available for Adenoid hypertrophy, which can cause aftereffects like recurrent respiratory

infections and allergic reactions. Chances of regrowth is also up to 26% and recurrence of some

symptoms are also reported in many cases. No conservative managements are available at present. So,

an alternate management protocol is a necessity.The selected treatment protocol includes Varanadi

Kashaya, Kanchanara guggulu tablet, Vilwadi tablet, Trikatukadi gandusham for one month followed

by 1 month of pathyakala with Saptamushtika yusha panam which has kaphahara properties. 23

patients diagnosed with non-infectious adenoid hypertrophy of age group 5-10 years selected on the

basis of inclusion criteria attending OPD and IPD of Shalakyatantra, Govt. Ayurveda College,

Thiruvananthapuram will be subjected to the selected treatment protocol for 30 days followed by 1

month of pathya. Clinical evaluation will be done prior to the commencement of intervention, 15th day,

30th day and 60th day. Results will be statistically analyzed after the study by Kruskal-wallis test.

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
5.00 Year(s) to 10.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Diagnosed cases of adenoid hypertrophy with breathing difficulty.
  • Patients between age group 5 years to 10 years, irrespective of gender, religion, and socio-economic status.

Exclusion Criteria

  • Diagnosed cases of systemic disorders like renal and cardiac diseases Diagnosed cases malignancy, TB, anemia and bleeding disorders.
  • Use of corticosteroids in all forms within 3 months of enrolment Participants with Infectious adenoid hypertrophy.
  • Malnourished and underweight children.
  • Children with developmental delay.

Outcomes

Primary Outcomes

To assess the effect of Varanadi Kashaya, Kanchanara guggulu tablet, Vilwadi tablet

Time Frame: 0th,30th,60th day

and Trikatukadi gandusha followed by Saptamushtika yusha pana and pathyahara and

Time Frame: 0th,30th,60th day

vihara in reducing the symptoms in participants of age group of 5-10 years irrespective

Time Frame: 0th,30th,60th day

of gender diagnosed with adenoid hypertrophy.

Time Frame: 0th,30th,60th day

Secondary Outcomes

  • To critically study adenoid hypertrophy in an Ayurvedic perspective.(0th,15th,30th, 60th day)

Investigators

Sponsor
Dr. Musafar Ahammed
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Musafar Ahammed

Government Ayurveda Medical College thiruvananthapuram kerala

Study Sites (1)

Loading locations...

Similar Trials