Post-Operative Pain prevention after hepato-pancreato-biliary surgery: continuoussUbfascial infiltration orePidural analgesia? a randomized controlled non-inferiority multicentertrial
Completed
- Conditions
- post-operative pain wound infiltrationwound catheterOBASepiduralhepato-pancreato-biliairy surgeryhpb surgerywondkatheterspancreas chirurgielever chirurgiegalweg chirurgie
- Registration Number
- NL-OMON23043
- Lead Sponsor
- AMC Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 102
Inclusion Criteria
Inclusion criteria
- Patients of 18 years and older
- Elective laparotomy for hepato-pancreato-biliary conditions:
„X Pylorus preserving pancreatoduodenectomy (PPPD), Whipple procedure
„X Distal pancreatectomy
„X Hepatojejunostomy
„X Partial liver resection
„X Other hepato-pancreato-biliary laparotomies (elective)
- Patients who have signed an informed consent form
Exclusion Criteria
- ASA status >3
- Chronic opioid use (>12 months) and not for the indication of this operation
- Allergy to local anesthetics or morphine
- Renal / Liver failure
- Contraindications for epidural placement
- INR >1.5, PPT>1.5, Platelets <80
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the Overall Benefit of Analgesic Score (OBAS) on day 1-5.
- Secondary Outcome Measures
Name Time Method