Reproducibility and Comparison of Digital Wavefront Sensing With Conventional Shack-Hartmann Wavefront Sensing: an Explorative Study
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- Qualitative description of lower order aberrations (LOA)
研究概览
简要总结
A holographic optical coherence tomography (H-OCT) setup is used to detect the wavefront by means of phase reconstruction.
详细描述
H-OCT will be tested in this study for its suitability for the qualitative investigation of aberrometry. We aim to achieve a digital equivalent for wavefront calculation of the widespread analog procedure commonly used with conventional wavefront-aberrometers. The results will be compared with those from a conventional analog wavefront calculation method.
In the course of this pilot study, 20 eyes of phakic and 10 eyes of pseudophakic subjects with suspected higher order aberrations will be examined using H-OCT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Informed consent
- •Men and women aged between 18 and 85 years
- •Normal ophthalmic findings except refractive errors or suspected higher order aberrations
- •Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
排除标准
- •Hyperopia > +6 Dpt. and Myopia < -6 Dpt.
- •Known ophthalmic diseases such as age related macular degeneration, diabetic retinopathy, glaucoma, retinal detachment or previous ocular trauma and surgeries except cataract extraction
- •Participation in a clinical trial in the previous 3 weeks
- •Presence of any abnormalities preventing reliable measurements as judged by the investigator
- •Pregnancy, planned pregnancy or lactating
研究组 & 干预措施
Holographic optical coherence tomography
Healthy phakic participants
干预措施: Holographic optical coherence tomography (Device)
结局指标
主要结局
Qualitative description of lower order aberrations (LOA)
时间窗: 14 +/- 3 days
Zernike terms, RMS-error, Strehl ratio
Qualitative description of higher order aberrations (HOA)
时间窗: 14 +/- 3 days
Zernike terms, root mean square error , Strehl ratio
次要结局
未报告次要终点
研究者
Doreen Schmidl
Doreen Schmidl [dschmidl]
Medical University of Vienna