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Clinical Trials/NCT03732053
NCT03732053
Completed
N/A

The Effectiveness of Physical Rehabilitation in the Enhancement of Proprioceptive and Cognitive Aspects on Alzheimer Disease Patients

Universidad Católica San Antonio de Murcia0 sites135 target enrollmentDecember 5, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Alzheimer's Type Dementia
Sponsor
Universidad Católica San Antonio de Murcia
Enrollment
135
Primary Endpoint
Cognitive Abilities Measurement
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This research study is developed on an experimental design with randomized controlled intervention were participated 135 subjects with AD including 45 of the control group. It lasted 6 months with pre-post tests (T0-T1) executed before and after six months of treatment. By having in focus the evaluation of GPR therapy effects on cognitive, proprioceptive, depressive, autonomy, gait and life quality of the above mentioned subjects.

Detailed Description

In order to assess the cognitive abilities of the patients a cognitive test was administered which acts through a scale concerning depression and mood evaluation as well as a questionnaire was developed aiming to evaluate the examined subjects' functional abilities: Mini Mental State Examination (MMSE), Quality of Life in Alzheimer Disease (QoL-AD), geriatric Depression Scale (GDS), Barthel Index (BI), Neuropsychiatric Inventory (NPI), Tinetti Scale (TS).

Registry
clinicaltrials.gov
Start Date
December 5, 2016
End Date
July 3, 2017
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Universidad Católica San Antonio de Murcia
Responsible Party
Principal Investigator
Principal Investigator

Jasemin Todri

PhD Candidate in Health Science

Universidad Católica San Antonio de Murcia

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis of Alzheimer's Disease
  • Older than 40 years of age
  • Male and female
  • Intellectual disability
  • Cognitive impairment
  • Able to do daily activities on his own
  • No presence of any other neurological and psychological disease
  • No presence of brain tumors

Exclusion Criteria

  • No presence of Alzheimer's Disease
  • Under 40 years old
  • Presence of brain tumors
  • Neurological patients
  • Presence of psychiatric disease
  • Depression symptoms
  • Presence of neuromuscular disease
  • Aggressive patients

Outcomes

Primary Outcomes

Cognitive Abilities Measurement

Time Frame: Change from baseline cognitive evaluation at 6'th month

The therapeutist provides the Mini Mental State Examination (MMSE) scale records. The evaluation consits in a 0-30 points-scale. Lower scores imply the severity of dementia.

Secondary Outcomes

  • Geriatric Depression Scale (GDS) Questionnaire(Change from baseline cognitive evaluation at 6'th month)
  • Barthel Index (BI)(Change from baseline cognitive evaluation at 6'th month)
  • Quality of Life in Alzheimer's disease (QoL-AD) Questionnaire(Change from baseline cognitive evaluation at 6'th month)
  • Neuropsychiatric Inventory (NPI)(Change from baseline cognitive evaluation at 6'th month)
  • Tinetti Scale (TS)(Change from baseline cognitive evaluation at 6'th month)

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