The Effectiveness of Physical Rehabilitation in the Enhancement of Proprioceptive and Cognitive Aspects on Alzheimer Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 135
- 主要终点
- Cognitive Abilities Measurement
研究概览
简要总结
This research study is developed on an experimental design with randomized controlled intervention were participated 135 subjects with AD including 45 of the control group. It lasted 6 months with pre-post tests (T0-T1) executed before and after six months of treatment. By having in focus the evaluation of GPR therapy effects on cognitive, proprioceptive, depressive, autonomy, gait and life quality of the above mentioned subjects.
详细描述
In order to assess the cognitive abilities of the patients a cognitive test was administered which acts through a scale concerning depression and mood evaluation as well as a questionnaire was developed aiming to evaluate the examined subjects' functional abilities: Mini Mental State Examination (MMSE), Quality of Life in Alzheimer Disease (QoL-AD), geriatric Depression Scale (GDS), Barthel Index (BI), Neuropsychiatric Inventory (NPI), Tinetti Scale (TS).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of Alzheimer's Disease
- •Older than 40 years of age
- •Male and female
- •Intellectual disability
- •Cognitive impairment
- •Able to do daily activities on his own
- •No presence of any other neurological and psychological disease
- •No presence of brain tumors
排除标准
- •No presence of Alzheimer's Disease
- •Under 40 years old
- •Presence of brain tumors
- •Neurological patients
- •Presence of psychiatric disease
- •Depression symptoms
- •Presence of neuromuscular disease
- •Aggressive patients
结局指标
主要结局
Cognitive Abilities Measurement
时间窗: Change from baseline cognitive evaluation at 6'th month
The therapeutist provides the Mini Mental State Examination (MMSE) scale records. The evaluation consits in a 0-30 points-scale. Lower scores imply the severity of dementia.
次要结局
- Geriatric Depression Scale (GDS) Questionnaire(Change from baseline cognitive evaluation at 6'th month)
- Barthel Index (BI)(Change from baseline cognitive evaluation at 6'th month)
- Quality of Life in Alzheimer's disease (QoL-AD) Questionnaire(Change from baseline cognitive evaluation at 6'th month)
- Neuropsychiatric Inventory (NPI)(Change from baseline cognitive evaluation at 6'th month)
- Tinetti Scale (TS)(Change from baseline cognitive evaluation at 6'th month)
研究者
Jasemin Todri
PhD Candidate in Health Science
Universidad Católica San Antonio de Murcia